Archive for April, 2008

Q

Saturday, April 26th, 2008

So, a local sales rep for a certain Qompany that sells mainly kits, but also robots, came by my office recently with a promotional flyer. An invitation, if you will, to a V.I.P. event - a showcase of their new robotic, liquid-handling, sample-preparing, all-singing, all-dancing box. A box with a lovely name, evocative of orchestras.

Now, I’ve made no bones in the past about not this not being my favourite of companies, their sales tactics ranging from dubious to downright annoying. And this fits right in… a V.I.P. event, you say? Then why, I ask, is it from 9:00 AM to 4:00 PM in a conference room? With refreshments all day? “Oh, don’t post this notice, I don’t want this open to everyone… just a select few.” They sure know how to make a fella feel special, I tells ya.

Oh, and the robot in question? Well, the sales rep described it to me as being a box that you can put any kind of sample into, and get any kind of prep out. Cells in, RNA out. Brain in, DNA out. Fossilized pterodactyl bones in, highly purified Jak Kinase out, that kind of thing.

I think I may give this one a miss.

Brand New Confusion

Saturday, April 12th, 2008

In this post-90’s biotech era which we all inhabit, I’m finding that brand recognition is becoming a confusing game indeed. Old favourite boutique vendors like Molecular Probes have been swallowed up by enormous, multi-tentacled distributors like Invitrogen, and keeping track of who’s distributing your favourite brand of pipettor, or water filter, or tissue culture media, can make for hours of fun and games. Even the big players keep getting bought and sold – just try to sort out the whole Merck/EMD fine chemical business, or the ownership structure of VWR, if you have some time to kill. And I’m still trying to get my head around Thermo Fisher. What does Thermo Electron have to do with distributing pipette tips and latex gloves? How, if at all, is this related to Thermo Finnigan? It makes my head hurt just thinking about it.

And then there’s my personal favourite suite of technologies du jour, loosely grouped into “next-generation” DNA sequencing, or NGS. Illumina buys Solexa, Applied Biosystems buys Agencourt Personal Genomics (but not Agenourt Bioscience, which is owned by Beckman Coulter – are you following this?), Roche gobbles up 454 Life Sciences. Pacific Biosciences is next, mark my words, with rumours of intense interest from Applied Biosystems, and probably many others. Helicos too, perhaps, so look for a merger or acquisition there, although with a market cap of $147 million and $50 million in the bank at the end of 2007, they could probably stay on their own for a while.

In the case of Illumina’s almost-works-most-of-the-time Genome Analyzer, most people still call it a “Solexa”. At the recent AGBT conference, which I’ve rattled on about in more detail elsewhere, practically the only people using the term “Illumina Genome Analyzer” were members of the large posse of Illumina employees in attendance. And most people don’t call the ex-454 machine a “Roche” GS-FLX; to most, it’s still a “454”, although this seems to me to be waning a bit under the crushing weight of Roche’s marketing machinery. Remarkably, the 454 Life Sciences website still exists, and is still a much, much better source of information on this NGS system than the Roche website, which is large, messy, and rather full of the 150,000 other things that Roche sells.

On the other hand, Applied Biosystems seems to have triumphed in branding their SOLiD system, and virtually nobody seems to remember that this was developed by Agencourt Personal Genomics and that the chemistry used was, for a time, referred to as the “APG process”, even by AB itself. Now it’s just SOLiD, small “i” and all, and the scientific community in general seems to have accepted that brand. Timing, I suppose, is everything.

Now, if someone could just explain to me why all these darn NGS boxes are blue

Bioscience Technologies

Wednesday, April 2nd, 2008

The latest email from them says this is my third and final notice. If I do not respond to this email they will terminate my subscription. Thank goodness.

This is one of those mailing lists I got on from a vendor show and don’t know how to get off of. I have my doubts whether not responding to the email will actually terminate the subscription but I’m keeping my fingers crossed.

These types of magazines might interest some but I don’t have any interest in thumbing through a magazine of advertisements.